Bunik, Victoria I : rechercher sur Z-Library

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1

Structure–function relationships in the 2-oxo acid dehydrogenase family: Substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins

Victoria I. Bunik, Dmitry Degtyarev

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2008

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2008

2

The multifaceted role of vitamin B 6 in cancer: Drosophila as a model system to investigate DNA damage

Contestabile, Roberto, di Salvo, Martino Luigi, Bunik, Victoria, Tramonti, Angela, VernÃ¬, Fiammetta

Journal:

Année:

2020

Fichier:

PDF, 849 KB

2020

3

The α-ketoglutarate-dehydrogenase complex

Gary E. Gibson, John P. Blass, M. Flint Beal, Victoria Bunik

Journal:

Molecular Neurobiology

Année:

2005

Langue:

english

Fichier:

PDF, 195 KB

english, 2005

4

Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-l-cysteine

Larry C.H. Park, Gary E. Gibson, Victoria Bunik, Arthur J.L. Cooper

Journal:

Biochemical Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 459 KB

english, 1999

5

Characterization of thioredoxins by sodium dodecyl sulfate-slab gel electrophoresis and high performance capillary electrophoresis

Dr. Victoria Bunik, Alexandra Shoubnikova, Hans Bisswanger, Hartmut Follmann

Journal:

ELECTROPHORESIS

Année:

1997

Langue:

english

Fichier:

PDF, 558 KB

english, 1997

6

Inhibitors of the α-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons

Sónia Sá Santos, Gary E. Gibson, Arthur J.L. Cooper, Travis T. Denton, Charles M. Thompson, Victoria I. Bunik, Paula M. Alves, Ursula Sonnewald

Journal:

Journal of Neuroscience Research

Année:

2006

Langue:

english

Fichier:

PDF, 378 KB

english, 2006

7

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

Victoria I. Bunik, Christian Sievers

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 390 KB

english, 2002

8

2-Oxo acid dehydrogenase complexes of multicellular organisms : Regulatory aspects

Victoria I. Bunik

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 55 KB

english, 2003

9

2-Oxo acid dehydrogenase complexes in redox regulation : Role of the lipoate residues and thioredoxin

Victoria I. Bunik

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 236 KB

english, 2003

10

Kinetic properties of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii : Evidence for the formation of a precatalytic complex with 2-oxoglutarate

Victoria Bunik, Adrie H. Westphal, Aart de Kok

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 751 KB

english, 2000

11

Homology Modelling of a Newly Discovered Thioredoxin Protein and Analysis of the Force Field and Electrostatic Properties

Günter Raddatz, Victoria I. Bunik, Thomas Scior, Hans Bisswanger

Journal:

Journal of Molecular Modeling

Année:

1997

Langue:

english

Fichier:

PDF, 133 KB

english, 1997

12

Enzyme-Catalyzed Side Reactions with Molecular Oxygen may Contribute to Cell Signaling and Neurodegenerative Diseases

Victoria I. Bunik, John V. Schloss, John T. Pinto, Gary E. Gibson, Arthur J. L. Cooper

Journal:

Neurochemical Research

Année:

2007

Langue:

english

Fichier:

PDF, 451 KB

english, 2007

13

Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels

Yulia M. Parkhomenko, Pavel A. Kudryavtsev, Svetlana Yu. Pylypchuk, Lilia I. Chekhivska, Svetlana P. Stepanenko, Andrej A. Sergiichuk, Victoria I. Bunik

Journal:

Journal of Neurochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 305 KB

english, 2011

14

Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart

Victoria Bunik, Thilo Kaehne, Dmitry Degtyarev, Tatiana Shcherbakova, Georg Reiser

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 379 KB

english, 2008

15

Phosphono Analogues of 2-Oxoglutarate Protect Cerebellar Granule Neurons upon Glutamate Excitotoxicity

Victoria I. Bunik, Maria S. Kabysheva, Eugeny I. Klimuk, Tatiana P. Storozhevykh, Vsevolod G. Pinelis

Journal:

Annals of the New York Academy of Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 310 KB

english, 2009

16

Structural determinants for the efficient and specific interaction of thioredoxin with 2-oxoacid dehydrogenase complexes

Guenter Raddatz, Volker Kruft, Victoria Bunik

Journal:

Applied Biochemistry and Biotechnology

Année:

2000

Langue:

english

Fichier:

PDF, 431 KB

english, 2000

17

Interaction of thioredoxins with target proteins: Role of particular structural elements and electrostatic properties of thioredoxins in their interplay with 2-oxoacid dehydrogenase complexes

Victoria Bunik, Günter Raddatz, Hans Bisswanger, Stephane Lemaire, Yves Meyer, Jean-Pierre Jacquot

Journal:

Protein Science

Année:

1999

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1999

18

Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons

Maria S. Kabysheva, Tatiana P. Storozhevykh, Vsevolod G. Pinelis, Victoria I. Bunik

Journal:

Biochemical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 647 KB

english, 2009

19

Role of 2-oxoglutarate dehydrogenase in brain pathologies involving glutamate neurotoxicity

Anastasia Graf, Maria Kabysheva, Eugeny Klimuk, Lidia Trofimova, Tatiana Dunaeva, Gregor Zündorf, Stefan Kahlert, Georg Reiser, Tatiana Storozhevykh, Vsevolod Pinelis, Natalia Sokolova, Victoria Bunik

Journal:

Journal of Molecular Catalysis B: Enzymatic

Année:

2009

Langue:

english

Fichier:

PDF, 667 KB

english, 2009

20

Increased catalytic performance of the 2-oxoacid dehydrogenase complexes in the presence of thioredoxin, a thiol–disulfide oxidoreductase

Journal:

Journal of Molecular Catalysis B: Enzymatic

Année:

2000

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2000

21

Thioredoxin reduction dependent on α-ketoacid oxidation by α-ketoacid dehydrogenase complexes

Victoria Bunik, Hartmut Follmann

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 436 KB

english, 1993

22

Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid

Victoria I. Bunik, Günter Raddatz, Ronald J.A. Wanders, Georg Reiser

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 331 KB

english, 2006

23

Up-regulation of 2-oxoglutarate dehydrogenase as a stress response

Graf, Anastasia, Trofimova, Lidia, Loshinskaja, Alexandra, Mkrtchyan, Garik, Strokina, Anastasiia, Lovat, Maxim, Tylicky, Adam, Strumilo, Slawomir, Bettendorff, Lucien, Bunik, Victoria I.

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2013

24

On the role of the mitochondrial 2-oxoglutarate dehydrogenase complex in amino acid metabolism

AraÃºjo, Wagner L., Trofimova, Lidia, Mkrtchyan, Garik, Steinhauser, Dirk, Krall, Leonard, Graf, Anastasia, Fernie, Alisdair R., Bunik, Victoria I.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 728 KB

english, 2013

25

Thiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease models

Bunik, Victoria I., Tylicki, Adam, Lukashev, Nikolay V.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 776 KB

english, 2013

26

Succinyl phosphonate, a protector of the 2-oxoglutarate dehydrogenase complex, corrects behavioral impairments in rats exposed to hypoxia or ethanol

Bunik, Victoria I., Lovat, Maxim, Groznaya, Alexandra, Graf, Anastasia, Dunaeva, Tatiana, Trofimova, Lidia, Sokolova, Natalia

Journal:

Alzheimer's & Dementia

Année:

2009

Langue:

english

Fichier:

PDF, 59 KB

english, 2009

27

Phosphonate Analogues of α-Ketoglutarate Inhibit the Activity of the α-Ketoglutarate Dehydrogenase Complex Isolated from Brain and in Cultured Cells †

Bunik, Victoria I., Denton, Travis T., Xu, Hui, Thompson, Charles M., Cooper, Arthur J. L., Gibson, Gary E.

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 133 KB

english, 2005

28

Thiamin-dependent enzymes: new perspectives from the interface between chemistry and biology

Bunik, Victoria I.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 56 KB

english, 2013

29

The RNA-binding protein HuR is essential for the B cell antibody response

Diaz-Muñoz, Manuel D, Bell, Sarah E, Fairfax, Kirsten, Monzon-Casanova, Elisa, Cunningham, Adam F, Gonzalez-Porta, Mar, Andrews, Simon R, Bunik, Victoria I, Zarnack, Kathi, Curk, Tomaž, Heggermont, Wa

Journal:

Nature Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 3.13 MB

english, 2015

30

Activation of Mitochondrial 2-Oxoacid Dehydrogenases by Thioredoxin

Bunik, Victoria, Follmann, Hartmut, Bisswanger, Hans

Journal:

Biological Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1997

31

Phosphonate Analogs of 2-Oxoglutarate Perturb Metabolism and Gene Expression in Illuminated Arabidopsis Leaves

Araújo, Wagner L., Tohge, Takayuki, Nunes-Nesi, Adriano, Daloso, Danilo M., Nimick, Mhairi, Krahnert, Ina, Bunik, Victoria I., Moorhead, Greg B. G., Fernie, Alisdair R.

Journal:

Frontiers in Plant Science

Année:

2012

Langue:

english

Fichier:

PDF, 4.32 MB

english, 2012

32

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis

Mkrtchyan, Garik, Aleshin, Vasily, Parkhomenko, Yulia, Kaehne, Thilo, Luigi Di Salvo, Martino, Parroni, Alessia, Contestabile, Roberto, Vovk, Andrey, Bettendorff, Lucien, Bunik, Victoria

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 3.48 MB

english, 2015

33

Inhibition of 2-Oxoglutarate Dehydrogenase in Potato Tuber Suggests the Enzyme Is Limiting for Respiration and Confirms Its Importance in Nitrogen Assimilation

Wagner L. Araújo, Adriano Nunes-Nesi, Sandra Trenkamp, Victoria I. Bunik and Alisdair R. Fernie

Journal:

PLANT PHYSIOLOGY

Année:

2008

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2008

34

Regulation of Catalysis Within Cellular Network: Metabolic and Signaling Implications of the 2-Oxoglutarate Oxidative Decarboxylation

Bunik, Victoria I., Strumilo, Slawomir

Journal:

Current Chemical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 238 KB

english, 2009

35

Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

Goncalves, Renata L.S., Bunik, Victoria I., Brand, Martin D.

Journal:

Free Radical Biology and Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2016

36

Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

Bunik, Victoria I., Fernie, Alisdair R.

Journal:

Biochemical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 633 KB

english, 2009

37

Tricarboxylic Acid Cycle Activity Regulates Tomato Root Growth via Effects on Secondary Cell Wall Production

Margaretha J. van der Merwe, Sonia Osorio, Wagner L. Araújo, Ilse Balbo, Adriano Nunes-Nesi, Eugenia Maximova, Fernando Carrari, Victoria I. Bunik, Staffan Persson and Alisdair R. Fernie

Journal:

PLANT PHYSIOLOGY

Année:

2010

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2010

38

Glutamate Excitotoxicity Induced by Nitric Oxide Mediated Dysfunction of the Mitochondrial 2-Oxoglutarate Dehydrogenase Complex

Weidinger, Adelheid, Moldzio, Rudolf, Törö, Gabor, Mkrtchyan, Garik, Dumitrescu, Sergiu, Trofimova, Lidia, Sole, Laia V Gili, Duvigneau, Johanna Catharina, Szabo, Csaba, Redl, Heinz, Bunik, Victoria,

Journal:

Free Radical Biology and Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 111 KB

english, 2017

39

Positive correlation between rat brain glutamate concentrations and mitochondrial 2-oxoglutarate dehydrogenase activity

Mkrtchyan, Garik V., Graf, Anastasia, Trofimova, Lidia, Ksenofontov, Alexander, Baratova, Ludmila, Bunik, Victoria

Journal:

Analytical Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 4.89 MB

english, 2018

40

Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

Bunik, Victoria I., Brand, Martin D.

Journal:

Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 794 KB

english, 2017

41

Mitochondrial Impairment May Increase Cellular NAD(P)H: Resazurin Oxidoreductase Activity, Perturbing the NAD(P)H-Based Viability Assays

Aleshin, Vasily, Artiukhov, Artem, Oppermann, Henry, Kazantsev, Alexey, Lukashev, Nikolay, Bunik, Victoria

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2015

42

Delayed Influence of Spinal Cord Injury on the Amino Acids of NO• Metabolism in Rat Cerebral Cortex Is Attenuated by Thiamine

Boyko, Alexandra, Ksenofontov, Alexander, Ryabov, Sergey, Baratova, Lyudmila, Graf, Anastasia, Bunik, Victoria

Journal:

Frontiers in Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2018

43

REDOX-DRIVEN SIGNALING: 2-OXO ACID DEHYDROGENASE COMPLEXES AS SENSORS AND TRANSMITTERS OF METABOLIC IMBALANCE

Bunik, Victoria

Journal:

Antioxidants & Redox Signaling

Année:

2018

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2018

44

Translating Enzymology into Metabolic Regulation: The Case of the 2- Oxoglutarate Dehydrogenase Multienzyme Complex

I. Bunik, Victoria, Raddatz, Guenter, Strumilo, Slawomir

Journal:

Current Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2013

45

Multiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological Implications

Bunik, Victoria, Artiukhov, Artem, Aleshin, Vasily, Mkrtchyan, Garik

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2016

46

A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent

Itkis, Yulia, Krylova, Tatiana, Pechatnikova, Natalia L., De Grassi, Anna, Tabakov, Vyacheslav Yu., Pierri, Ciro Leo, Aleshin, Vasiliy, Boyko, Aleksandra, Bunik, Victoria I., Zakharova, Ekaterina Yu.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2019

47

Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Wagner, Tristan, Boyko, Alexandra, Alzari, Pedro M., Bunik, Victoria I., Bellinzoni, Marco

Journal:

Journal of Structural Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2019

48

Benefits of Thiamin (Vitamin B1) Administration in Neurodegenerative Diseases may be Due to Both the Coenzyme and Non-coenzyme Roles of Thiamin

Bunik, Victoria I

Journal:

Journal of Alzheimer's Disease & Parkinsonism

Année:

2014

Fichier:

PDF, 470 KB

2014

49

Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration

Aleshin, Vasily A, V Mkrtchyan, Garik, Kaehne, Thilo, V Graf, Anastasia, V Maslova, Maria, I Bunik, Victoria

Journal:

Journal of Neurochemistry

Année:

2019

Fichier:

PDF, 3.45 MB

2019

50

Hypoxic Adaptation of Mitochondrial Metabolism in Rat Cerebellum Decreases in Pregnancy

Graf, Anastasia, Trofimova, Lidia, Ksenofontov, Alexander, Baratova, Lyudmila, Bunik, Victoria

Journal:

Année:

2020

Fichier:

PDF, 686 KB

2020